RHU Shiva

30 septembre 2022

Stroke genetics informs drug discovery and risk prediction across ancestries

The largest study on stroke genetics with more than 2M individuals (incl. >200,000 cases) has just been published in Nature! The GIGASTROKE project engaged numerous cohorts from across the […]
13 septembre 2022

Official launch of the SHIVA cohort

After the French ethics committee approval, the SHiVA cohort initiation visit held last week at the CHU de Bordeaux with the members actively involved in the […]
27 juillet 2022

#5 SHIVA Scientific Mini-symposium_ Sept 29, 2022

The next scientific symposium will be held on the September, 29th. Ilana Caro, phD fellow in ELEANOR team, will present the mendelian ranodmization of pQTLs from […]
10 mai 2022

Active presence of SHIVA members at ESOC 2022!

The 8th European Stroke Organisation Conference took place from 4 – 6 May 2022 at Lyon.Prof. Stéphanie Debette presented how stroke genetics contributes to drug discovery […]
4 mai 2022

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Aniket Mishra, Cécile Duplaà, Dina Vojinovic, Hideaki Suzuki, Muralidharan Sargurupremraj, Nuno R Zilhão, Shuo Li, Traci M Bartz, Xueqiu Jian, Wei Zhao, Edith Hofer, Katharina Wittfeld, […]
4 mai 2022

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Authors Aniket Mishra, Cécile Duplaà, Dina Vojinovic, Hideaki Suzuki, Muralidharan Sargurupremraj, Nuno R Zilhão, Shuo Li, Traci M Bartz, Xueqiu Jian, Wei Zhao, Edith Hofer, Katharina […]
3 mai 2022

Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives

Debette S, Markus HS. Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives. Circ Res. 2022;130(8):1095-1111. doi:10.1161/CIRCRESAHA.122.319950
3 mai 2022

Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives

Debette S, Markus HS. Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives. Circ Res. 2022;130(8):1095-1111. doi:10.1161/CIRCRESAHA.122.319950
3 mai 2022

Wnt/frizzled Signaling in Endothelium: A major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity

Bats ML, Peghaire C, Delobel V, Dufourcq P, Couffinhal T and Duplàa C. (2022). Cold Spring Harb Perspect Med . 2022 Jan 24;a041219. doi: 10.1101/cshperspect.a041219. Online […]
3 mai 2022

Wnt/frizzled Signaling in Endothelium: A major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity

Bats ML, Peghaire C, Delobel V, Dufourcq P, Couffinhal T and Duplàa C. (2022). Cold Spring Harb Perspect Med . 2022 Jan 24;a041219. doi: 10.1101/cshperspect.a041219. Online […]
14 février 2022

The annual follow-up of the i-Share cohort is completed, its ancillary study SHIVA-Share continues

Over the past 9 years, with more than 21,000 participants, the i-Share cohort has become the benchmark for research on student health. A large amount of […]
13 janvier 2022

1st Scientific Advisory Board meeting

13 janvier 2022

RHU SHIVA General Assembly took place on the 13-14 Jan 2022

The General Assembly took place online on the 13-14 January 2022 with the presence of SHIVA Scientific Advisory Board. Thank you to the participants and the […]
4 janvier 2022

RHU SHIVA General Assembly, 13-14 Jan 2022

The General Assembly (GA) of the RHU SHIVA will take place during the 13th-14th January 2022. In the context of the current health crisis, the GA […]
3 janvier 2022

Genetics of common cerebral small vessel disease

Debette S, Bordes C., Sargurupremraj M., Mishra A. Nat Rev Neurol. (2022). https://doi.org/10.1038/s41582-021-00592-8
3 janvier 2022

Genetics of common cerebral small vessel disease

Bordes C, Sargurupremraj M, Mishra A, Debette S. Nat Rev Neurol. (2022). https://doi.org/10.1038/s41582-021-00592-8
3 janvier 2022

Comprehensive gene-mapping study of extreme MRI-defined cerebral small vessel disease reveals TRIM47 as a strong candidate

Mishra A*, Duplaà C*,Vojinovic D*, Suzuki H*, Sargurupremraj M*, (…), Soumare A, Smith JA, Knopman DS, Morris Z, Zhu Y, Rotter JI, Dufouil C, (…), Ihara […]
3 janvier 2022

Genomic studies across the lifespan point to early mechanisms determining subcortical volumes

Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumaré A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli […]
3 janvier 2022

Genomic studies across the lifespan point to early mechanisms determining subcortical volumes

Le Grand Q, Satizabal CL, Sargurupremraj M, Mishra A, Soumaré A, Laurent A, Crivello F, Tsuchida A, Shin J, Macalli M, Singh B, Beiser AS, DeCarli […]
3 janvier 2022

Age-Related Variations in Regional White Matter Volumetry and Microstructure During the Post-adolescence Period: A Cross-Sectional Study of a Cohort of 1,713 University Students

Tsuchida A, Laurent A, Crivello F, Petit L, Pepe A, Beguedou N, Debette S, Tzourio C, Mazoyer B. Front Syst Neurosci. 2021 Aug 3;15:692152. doi: 10.3389/fnsys.2021.692152. […]
3 janvier 2022

Age-Related Variations in Regional White Matter Volumetry and Microstructure During the Post-adolescence Period: A Cross-Sectional Study of a Cohort of 1,713 University Students

Tsuchida A, Laurent A, Crivello F, Petit L, Pepe A, Beguedou N, Debette S, Tzourio C, Mazoyer B. Front Syst Neurosci. 2021 Aug 3;15:692152. doi: 10.3389/fnsys.2021.692152. […]
15 décembre 2021

4th meeting of the SHIVA Executive Committee

14 décembre 2021

5th meeting of the SHIVA Business Liaison Committee

10 décembre 2021

RHU SHIVA is recruiting a Hospital Assistant

Within a team of several investigators from the Memory Center and of the Cardiology Department of the Bordeaux University Hospital, the recruited doctor will be in […]
7 décembre 2021

5th meeting of the SHIVA Ethics Advisory Board