RHU Shiva

25 septembre 2023

Genetic Insights on the Relation of Vascular Risk Factors and Cervical Artery Dissection

Quentin Le Grand, Leslie Ecker Ferreira, Tiina M. Metso, Sabrina Schilling, Turgut Tatlisumak, Caspar Grond-Ginsbach, Stefan T. Engelter, Philippe Lyrer, Jennifer J. Majersik, Bradford B. Worrall, […]
21 septembre 2023

Dementia prevention at the « Rencontre Francophone sur la Maladie d’Alzheimer et les syndromes apparentés » 2023

The 16th French conference « Rencontre Francophone sur la Maladie d’Alzheimer et les syndromes apparentés » 2023, took place at Bordeaux from 18 to 20 September. These Conferences […]
27 juillet 2023

SHIVA at the Organization for Human Brain Mapping (OHBM) Annual meeting 2023

Members of the RHU SHIVA project have participated to the 29th Organization for Human Brain Mapping Annual meeting 2023 (OHBM2023). Dr. Ami Tsuchida, SHIVA researcher in the GIN […]
21 juillet 2023

SHIVA at the Alzheimer’s Association International Conference 2023, in Amsterdam

Stéphanie Debette presented the work on « Extending understanding of the genetic architecture of cerebral small vessel disease using advanced imaging measures in CHARGE & UK Biobank » […]
1 juillet 2023

Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels

Munsch G, Proust C , Labrouche-Colomer S, Aïssi D, […], Smadja DM, Jacqmin-Gadda H, Trégouët DA. Genome-wide association study of a semicontinuous trait: illustration of the […]
13 juin 2023

#7 SHIVA Scientific Mini-symposium – June 13, 2023

The 7th SHIVA Scientific Mini-Symposium has been held online today for a discussion with a special guest, Professor Tao Wang (University of Manchester), on the application of the iPSC model to […]
19 mai 2023

VBHI University Hospital Institute, awarded by the France 2030 call for IHU projects

The SHIVA consortium is delighted to announce that SHIVA investigators will launch the VBHI University Hospital Institute, led by Debette Stéphanie coordinated by Bordeaux University and […]
11 mai 2023

The SHIVA project in Boston and 2 CHARGE Awards!

Prof. Stéphanie Debette (the SHIVA coordinator), Dr David-Alexandre Trégouët (WP2 leader in SHIVA), Dr. Marie-Gabrielle Duperron (SHIVA researcher and physician), Dr Aniket Mishra (genetic epidiomiologist in […]
28 avril 2023

2nd Scientific Advisory Board meeting

17 avril 2023

A SHIVA publication in Nature Medicine : A large genomic study on perivascular space burden unravels early mechanisms of cerebral small vessel disease.

Cerebral small vessel disease is a leading cause of stroke and dementia for which no mechanism-based drugs are currently available. The first genomic study on perivascular […]
13 avril 2023

« Genetic entries into Vascular Cognitive Disorders pathobiology », a webinar organized by the Alzheimer’s Association ISTAART

The Alzheimer’s association ISTAART organizes a webinar on « Genetic entries into Vascular Cognitive Disorders pathobiology« , in which the SHIVA coordinator, Stéphanie Debette, is panelist. This Professional […]
27 mars 2023

RHU SHIVA General Assembly, 23-24 March 2023

The RHU SHIVA General Assembly took place online on the 23rd and 24th of March 2023 with the presence of members of the SHIVA Scientific Advisory […]
2 mars 2023

SHIVA at the International Stroke Genetics Consortium workshop in Melbourne

Prof. Stephanie Debette presented advances on cSVD multiomics analyses within the SHIVA framework presented at the International Stroke Genetics Consortium workshop in Melbourne. The workpackage 2 […]
19 janvier 2023

Prof. Thierry Couffinhal awarded with the « Fondation pour la Recherche Médicale » price 2022

Professor Thierry Couffinhal, co-coordinator of the RHU SHIVA, is a cardiologist at the Bordeaux University Hospital and heads the Biology of Cardiovascular Diseases unit at the […]
30 novembre 2022

The first SHIVA student to obtain a PhD degree!

We congratulate Quentin Le Grand (ELEANOR-BPH) for his excellent PhD dissertation on the “Genetic determinants of structural and vascular brain phenotypes in young adults and across […]
29 novembre 2022

#6 SHIVA Scientific Mini-symposium – Nov 29, 2022

The 6th SHIVA scientific symposium has been held on the November, 29th. Frauke Beyer, post-doctorant fellow in ELEANOR team (BPH U1219), presented the development of a […]
17 novembre 2022

First inclusion in the SHIVA cohort!

During the site initiation visit of the Assistance Publique – Hôpitaux de Paris site, Prof. Olivier HANON from Broca Hospital included with his team the first […]
13 octobre 2022

Stroke genetics informs drug discovery and risk prediction across ancestries

The largest study on stroke genetics with more than 2M individuals (incl. >200,000 cases) has just been published in Nature! The GIGASTROKE project engaged numerous cohorts from across the […]
30 septembre 2022

Stroke genetics informs drug discovery and risk prediction across ancestries

The largest study on stroke genetics with more than 2M individuals (incl. >200,000 cases) has just been published in Nature! The GIGASTROKE project engaged numerous cohorts from across the […]
13 septembre 2022

Official launch of the SHIVA cohort

After the French ethics committee approval, the SHiVA cohort initiation visit held last week at the CHU de Bordeaux with the members actively involved in the […]
27 juillet 2022

#5 SHIVA Scientific Mini-symposium_ Sept 29, 2022

The next scientific symposium will be held on the September, 29th. Ilana Caro, phD fellow in ELEANOR team, will present the mendelian ranodmization of pQTLs from […]
10 mai 2022

Active presence of SHIVA members at ESOC 2022!

The 8th European Stroke Organisation Conference took place from 4 – 6 May 2022 at Lyon.Prof. Stéphanie Debette presented how stroke genetics contributes to drug discovery […]
4 mai 2022

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Aniket Mishra, Cécile Duplaà, Dina Vojinovic, Hideaki Suzuki, Muralidharan Sargurupremraj, Nuno R Zilhão, Shuo Li, Traci M Bartz, Xueqiu Jian, Wei Zhao, Edith Hofer, Katharina Wittfeld, […]
4 mai 2022

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Authors Aniket Mishra, Cécile Duplaà, Dina Vojinovic, Hideaki Suzuki, Muralidharan Sargurupremraj, Nuno R Zilhão, Shuo Li, Traci M Bartz, Xueqiu Jian, Wei Zhao, Edith Hofer, Katharina […]
3 mai 2022

Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives

Debette S, Markus HS. Stroke Genetics: Discovery, Insight Into Mechanisms, and Clinical Perspectives. Circ Res. 2022;130(8):1095-1111. doi:10.1161/CIRCRESAHA.122.319950