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NEWS

EVENTS

PUBLICATIONS

14 avril 2025

Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification

We are thrilled to announce our latest publication in Alzheimer’s & Dementia. In addition to the well-known APOE locus, polygenic risk scores for dementia have potential […]

3 avril 2025

RHU SHIVA General Assembly, 3-4 April 2025

On the 3rd and 4th April 2025, we had the privilege of organising the General Assembly of the RHU SHIVA project. This gathering brought together consortium […]

20 décembre 2024

Stéphanie Debette joins the Académie des Sciences!

Stéphanie Debette, the SHIVA coordinator, is joining the prestigious French Académie des sciences. The Académie des sciences supports research, science education and scientific life as a […]

13 septembre 2024

We are hiring 2 post-doctoral researcher genetic epidemiology

Would you like to contribute to a major project aimed at slowing cognitive decline and preventing dementia? Join the Bordeaux Population Health Center (BPH, U1219 Univ. […]

31 mai 2024

Diffusion imaging genomics provides novel insight into early mechanisms of cerebral small vessel disease.

Quentin Le Grand, Ami Tsuchida, Alexandra Koch, Mohammed-Aslam Imtiaz, N. Ahmad Aziz, Chloé Vigneron, Laure Zago, Mark Lathrop, Alexandre Dubrac, Thierry Couffinhal, Fabrice Crivello, Paul M. […]

17 mai 2024

RHU SHIVA at the European Stroke Organisation Conference 2024 and Ilana Caro Young Research Investigator awardee

The RHU SHIVA project was represented at the European Stroke Organisation Conference 2024 at Basel (Switzerland) with Prof. Debette Stéphanie, Ilana Caro, Tim D’Aoust and Dr […]

13 juin 2023

#7 SHIVA Scientific Mini-symposium – June 13, 2023

The 7th SHIVA Scientific Mini-Symposium has been held online today for a discussion with a special guest, Professor Tao Wang (University of Manchester), on the application of the iPSC model to […]

28 avril 2023

2nd Scientific Advisory Board meeting

27 mars 2023

RHU SHIVA General Assembly, 23-24 March 2023

The RHU SHIVA General Assembly took place online on the 23rd and 24th of March 2023 with the presence of members of the SHIVA Scientific Advisory […]

29 novembre 2022

#6 SHIVA Scientific Mini-symposium – Nov 29, 2022

The 6th SHIVA scientific symposium has been held on the November, 29th. Frauke Beyer, post-doctorant fellow in ELEANOR team (BPH U1219), presented the development of a […]

27 juillet 2022

#5 SHIVA Scientific Mini-symposium_ Sept 29, 2022

The next scientific symposium will be held on the September, 29th. Ilana Caro, phD fellow in ELEANOR team, will present the mendelian ranodmization of pQTLs from […]

13 janvier 2022

1st Scientific Advisory Board meeting

1 mai 2024

Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia

Sargurupremraj M, Soumaré A, Bis JC, Surakka I, Jürgenson T, Joly P, Knol MJ, Wang R, Yang Q, Satizabal CL, Gudjonsson A, Mishra A, Bouteloup V, […]

20 décembre 2023

Early detection of white matter hyperintensities using SHIVA-WMH detector

Tsuchida A, Boutinaud P, Verrecchia V, Tzourio C, Debette S, Joliot M. Early detection of white matter hyperintensities using SHIVA-WMH detector. Hum Brain Mapp. 2023 Dec […]

25 septembre 2023

Genetic Insights on the Relation of Vascular Risk Factors and Cervical Artery Dissection

Quentin Le Grand, Leslie Ecker Ferreira, Tiina M. Metso, Sabrina Schilling, Turgut Tatlisumak, Caspar Grond-Ginsbach, Stefan T. Engelter, Philippe Lyrer, Jennifer J. Majersik, Bradford B. Worrall, […]

1 juillet 2023

Genome-wide association study of a semicontinuous trait: illustration of the impact of the modeling strategy through the study of Neutrophil Extracellular Traps levels

Munsch G, Proust C , Labrouche-Colomer S, Aïssi D, […], Smadja DM, Jacqmin-Gadda H, Trégouët DA. Genome-wide association study of a semicontinuous trait: illustration of the […]

17 avril 2023

A SHIVA publication in Nature Medicine : A large genomic study on perivascular space burden unravels early mechanisms of cerebral small vessel disease.

Cerebral small vessel disease is a leading cause of stroke and dementia for which no mechanism-based drugs are currently available. The first genomic study on perivascular […]

13 octobre 2022

Stroke genetics informs drug discovery and risk prediction across ancestries

The largest study on stroke genetics with more than 2M individuals (incl. >200,000 cases) has just been published in Nature! The GIGASTROKE project engaged numerous cohorts from across the […]

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